Lactobacillus paracasei ST11, I-1572, LPC-37... Benefits and Uses

Lactobacillus paracasei is a probiotic bacterium within the group of live lactobacilli. There are different strains or subspecies with health benefits such as L. paracasei ST11, Shirota, CNCM I-1572, lpc-37, and LP-33, all of which are similar in their medicinal properties and have effects on the regulation of intestinal flora and the processing of food in the intestines, though each serves a specific purpose.

While there are some differences between the various subspecies of this microorganism, most of their effects are consistent across all of them, showing a certain predisposition to be used as a probiotic in specific cases.

Types of Lactobacillus paracasei

This bacterium, which you can buy as a probiotic, acts as a host in the human intestine, producing various benefits for the body.

It belongs to the group of gram-positive bacteria, being heterofermentative and also considered a lactic acid bacterium.

Its activity in the human body is through symbiosis or commensalism, meaning it lives inside the body benefiting from it while the person also benefits from a certain number of bacteria.

L. paracasei ST11

We can find this variety in different commercial products that serve to complement nutrition and strengthen the intestinal flora. Some of them are dedicated to scalp care like Innéov Duology 2 in 1, or as pills in other types of supplements and vitamin complexes.

The benefits of Lactobacillus paracasei ST11 are for diarrhea caused by rotavirus, reducing and shortening the time it is present in the adult or child who starts taking the probiotic bacterium orally.

Another probiotic with powerful and healthy effects for the digestive system is Lactobacillus rhamnosus GR-1, LGG, and other strains that we explain and recommend you see if you are interested in caring for the intestinal flora and the entire human microbiota. L. rhamnosus is a common species in commercial probiotics, perhaps the most consumed along with L. acidophilus LA-14 and DDS-1.

L. paracasei shirota

Its name derives from Yakult, a type of drinkable yogurt made from fermented milk.

Like the other strains of lactobacillus paracasei, it belongs to the Lactobacillus group and acts in the human intestine.

Its properties and benefits are for the intestinal flora, increasing it while being part of it and inhibiting the growth of microorganisms that can be harmful to health.

If you want to know all the details, we recommend that you read the complete information about Lactobacillus casei as in this text you will find everything it can do for you.

L. paracasei CNCM I-1572

With scientific evidence of its benefits and analyses on Irritable Bowel Syndrome (IBS), Lactobacillus paracasei CNCM I-1572 is a variety of the probiotic that gives it its name, i.e., L. paracasei.

Although studies have not been able to prove that it reduces IBS symptoms, abdominal pain, and common symptoms of this pathology, it has been evidenced that it reduces the growth of Ruminococcus bacteria from the Clostridia class, as well as the pro-inflammatory cytokine interleukin, indicating that it may be viable to control inflammation in certain cases.

If you are interested in a probiotic with beneficial effects for irritable bowel, you can also see Lactobacillus plantarum 299v as it has advantages over others. Another very interesting option is Lactobacillus reuteri, which, like plantarum, is well-tested and validated, being among the most used in the world.

L. paracasei LPC-37

Another probiotic Lactobacillus paracasei subsp. patented as LPC-37 and isolated from dairy sources.

This variety is used for commercial purposes and has been developed with funding from the EU and PROSAFE.

It withstands gastric acids well, maintaining a considerable number after coming into contact with bile, which is why it can be taken orally since a large number of these bacteria will reach the intestine without degrading. It tolerates low pH and has high bile salt tolerance.

Its adherence to the intestinal mucosa is good, allowing it to bind to the host's intestine without difficulty. This can modulate the immune system and control pathogens that usually colonize the intestines such as Salmonella typhimurium, Staphylococcus aureus, Escherichia coli, Listeria monocytogenes, etc.

L. paracasei LP-33

This variety has been studied in cases of allergic rhinitis and where there is an imbalance between Th1 and Th2 cells.

Lactobacillus paracasei LP-33 is capable of significantly reducing the symptoms and side effects of people allergic to grass pollen.

Although the data is preliminary, more studies are needed to conclude that the beneficial effects apply to the entire population affected by allergic rhinitis, the reports obtained indicate that it could be a very important line of study for many types of allergies caused by grasses.

Benefits it may have

On one hand, being present among the millions of organisms that make up the human microbiota, it produces the secretion of a special polysaccharide that strengthens the immune system.

We also find that its presence in the intestinal mucosa is beneficial by competing with other bacteria that can cause infection. Thus, being present along with other live paracasei lactobacilli inhibits their growth, a characteristic that gives it great power to better assimilate food, reduce the side effects of lactose, and regulate intestinal transit and bowel movements in both healthy people and those suffering from episodes of diarrhea and constipation.

According to studies conducted by the University of Milan, the results are excellent because, when exposing immune cells to the polysaccharide produced by L. paracasei, these increase the secretion of pro-inflammatory cytokines and chemokines, which is why caution is recommended in cases of inflammatory and degenerative diseases as it could worsen them. Examples of these are infections caused by Helicobacter pylori, stomach ulcers, and ulcerative colitis, to name a few.

These data on the benefits of Lactobacillus paracasei and its contraindications and side effects are very important because many bacteria of the Lactobacillus class have the opposite effect, and in many of these cases, other probiotics like Lactobacillus gasseri or taking them from natural sources like yogurt with Lactobacillus bulgaricus are recommended.

However, in the case of L. paracasei we should avoid taking the probiotic in these situations, except in cases where it is expressly recommended by a specialist.

According to consulted sources, while it is true that the pro-inflammatory response is lower than that produced by other types of bacteria, we should always consider its activation.

In the case of fermented dairy products, it is used similarly to other lactobacilli. Paracasei probiotic is a lactic bacterium, functioning as an agent for fermentation and production of lactic acid.

Lactobacillus paracasei vs casei: Are There Differences?

Their names often cause confusion as they are very similar. In practice, they are considered different species of lactic bacteria, meaning that although they seem the same by their designation, they are not.

Lactobacillus paracasei vs casei can be compared without any inconvenience as they are distinct microorganisms.

Their taxonomic group is closely related, being within the heterofermentative lactobacilli. To differentiate Lactobacillus casei and L. paracasei, it is necessary to conduct a study under the microscope or work on the V1 region of the 16S rRNA gene.

If you have more questions about their health benefits and differences, you can leave us your inquiry or access the text we have indicated where you will find all the answers about L. casei.

Commercial Names of L. paracasei

• LC11.
• F19.
• 431.
• Brap-01.
• La 802.
• MCC1849.
• NCC 2461.
• CBA L74.
• 8700 2.

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Other Related Lactobacilli

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References